Talk:Myofibroblast

Anatomy: Microanatomy Mid‑importance

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any references?

More dysfunction. edit

Latest comment: 11 months ago1 comment1 person in discussion

In addition to interference in cardiac propagation of electrical signals, an article I am reading states the following:

"The excessive subepithelial collagen deposition is located beneath the basement membrane and seems to be caused by myofibroblast dysfunction, leading to collagen overproduction with ECM-remodeling, as well as an imbalance between fibrogenesis and fibrinolysis which results in an impaired degradation of ECM proteins."

'Lack of autoantibodies against collagen and related proteins in collagenous colitis.' Larsson, JK; Roth, B; Ohlsson, B; and Sjoberg, K.

BMC Immunology - {2022} 23:29
(peer-revieved original papers published by open-source BioMed Central on SpringerLink) https://doi.org/10.1186/s12865-022-00504-5
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In other words, myofibroblast dysfunction seems to cause collagenous colitis. Ouch! Thank you for your time, Wordreader (talk) 20:02, 21 May 2023 (UTC)Reply

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