Talk:MyoD

Untitled

I'm not sure that MyoD makes satellite cells drop out of the cell cycle (as is currently written). I'll look it up when I get a chance. Dr Aaron 14:02, 1 November 2006 (UTC)

Expansion

I may expand this article substantially for a Honors College Development Biology project and I think a good place to start would be adding a mechanism section and summarizing some of the interactions and pathways. These are both potential expansions. Mhirabay (talk) 04:57, 8 February 2015 (UTC)

Proposed Outline

• History
• Function
• Biological sources
• Mechanisms
• Role in the wnt signaling pathway
• Interactions
• Coactivators

Mhirabay (talk) 20:37, 21 February 2015 (UTC)

Comments By Lauren

• Overall a really awesome job
• Maybe reword the first paragraph it is very detailed and could use some simplification, considering most people will probably only read the first paragraph or two
• For paragraph two is that citation for the entire paragraph, maybe considering adding additional citations through out to strengthen the evidence and possible citing multiple papers
• Maybe say Published on October 21st
• There are no citations in the function section
• Function section: citation particularly needed when talking about the additional role in regulating muscle repair since it is not exactly known
• Add blue link thing to feed forward in the function section as some people may not be as familiar
• Keep constant labeling of protein names such as SETDB1. Sometimes it is capitalized and other times it is lower case even when not referring to a mutant strand (mutants are always lower case, generally) Mechanism section
• Citation needed after last section of paragraph 2 in mechanism section
• Wnt section is really strong, possibly add more citations. I think adding citations will really help strengthen everything
• But every citation I have checked has been spot on so great work!!
• To interactions add the ones that don't have a wikipedia page as well maybe, in case one is ever created it for it or something
• Really like the data box at the to, very detailed
• Your page is really impressive and the number of citations is awesome. I would just incorporate the use of citations more overall
• Some small grammatical errors here and there so read through word for word to catch them
• Some places need commas and they're aren't any
• If you want me to go through it I can, I didn't want to mess with your sandbox
• Really like the suggested readings section
• Also you use a lot of high level detail maybe simplify the intro and the major points in the sections, most people reading this will probably be familiar with biology overall and understand it but sometimes I think it helps to simplify to an 8th grade level for the big parts so the average person coming across your page can understand the overall idea if that ever happens

Lnbond92 (talk) 02:58, 10 April 2015 (UTC)

Comments from Jiyao

• Great article only needs some minor modification
• A few wikilinks could be added. Like "promoter","phosphorylation","Paracrine signalling","lympoid enhaner factor","enhancer","NAFC1"... a few of them I have added for you.
• A few typos and I have fixed them for you
• You made a very straightforward mechanism figure although I think if the text would surrounded or right beside the picture would be better (not too much white space makes it look compact）
• For the mechanism part, I suggest if you divided them into a few subsection will lead to better readability. Like "Function of KAP1" "Function of SetDB1" （if too much words are clustered together, people usually don't feel like reading it all the way through）
• Also,for the format of gene protein names, if it's human gene, it should be all cap and in italics; if it's human protein it should be all caps and in regular font
• Overall you've done an excellent job, learned a lot from your article!

JiyaoZ (talk) 17:45, 29 April 2015 (UTC)

Comments from Ayebeesung

• Excellent article and very thorough with everything. Looks great.
• "MyoD is known to have binding interactions with hundreds of muscular gene promoters and drive myoblast proliferation"...I think it should be "to drive" to make the sentence paralleled.
• You should maybe link "KRAB" with this: https://en.wikipedia.org/wiki/Kr%C3%BCppel_associated_box — Preceding unsigned comment added by Ayebeesung (talk • contribs) 13:34, 11 May 2015 (UTC)