note edit

The link in Note 3, http://familydoctor.org/online/famdocen/home/common/pain/disorders/616.html is broken, because the article has moved to http://familydoctor.org/online/famdocen/home/common/bone/616.html. Can this be updated? Thank you. Usableweb (talk) 15:57, 10 June 2011 (UTC)Reply

Suggest Merge edit

This article should be merged with Arthritis, as it is virtually identical, except it focuses on the knee. If Arthritis of the knee's were significantly different than Arthritis of the say, elbow or hand, than it would make sense to have a separate article. Since there is virtually no difference in symptoms, prognosis and treatment of Arthritis of any part of the body, it makes no sense to have an article for Arthritis affecting individual limbs. The "Treatment" sub-section is more detailed than that of Arthritis, I recommend it is merged with the "Treatment" sub-section of the parent article Arthritis. LiamSP (talk) 06:24, 30 December 2010 (UTC)Reply

Biological Treatments edit

This article fails to include any new-age treatments. These included articular cartilage stem cell paste graft, that which had a high success rate, succeeding 70% for those afflicted by arthritis (Stone et al.). Other options include autologous blood (e.g. platelet-rich plasma; PRP) therapy or autoloogus stem cell therapy(ASCT). ASCT has been supported by at least 1 paper in which a mildly degenerated knee of an older woman (at least in her 50's) avoided joint replacement.

Such cases are becoming increasingly common with the surgery of Regen treatment centers. Buyer beware, many of these centers are profit-motivated. One of the most credible centers is that of Regenexx in Denver, CO. This center regularly publishes clinical-date and is very research-orientated; they also have some of the best prices (Note: I am NOT affiliated with Regnexx).

Still alternative treatments include fresh osteochondral allograft for younger patients. A expert in this field includes Bill Bugbee, among others.

A promising, but controversial treatment is that of Dr. Alan R. Dunn of Miami. It involves intra-articular injection of human growth hormone (IAGH). It is seeded from the observation that acromegaliacs routinely have twice the normal density than a non-acromegliac. Dunn notes IAGH causes morphoangiogenesis of the cartilage cells resulting in fetal-like (scar-free) healing (2002; www.iagh.com). Noted orthopedist researcher Eric Strauss presented a study that concluded IAGH combined with marrow stimulation techniques resulted in better repair tissue in an animal model. Human trials will take place soon. Note that Dunn has been applying IAGH for 15 years as have noted prolotherapists (e.g. Ross Hauser; www.caringmedical.com) whom have picked up on the technique. Dunn claims a 75% success rate in knees.

Autologous Chondrocyte Implantation (ACI; Carticel; Genzyme) is effective for unicompartmental arthritis in some cases. Micro or macrofracture are effective techniques for cartilage regeneration as is abrasion arthroplasty (they all fall under the window of marrow stimulation techniques).

Saw et al. has done a study showing that microfracture + blood-based stem cells increases outcomes in early-stage arthritis.

The future of biological based cartilage repair resides in these standard cartilage repair techniques in combination with growth factors (HA, IAGH, Stem Cells, PRP, etc.).

[Note: I am not educated in wikicode so hopefully an experienced user can consolidate and find the necessary sources for the information above] — Preceding unsigned comment added by 2001:5B0:26FF:2EF0:0:0:0:36 (talk) 13:57, 4 October 2013 (UTC)Reply

Proposal for deletion of the article Knee arthritis edit

Hi. I'm nominating this article for deletion. As LiamSP noted above, much of the content in the article deals with arthritis in general. I had just recently reviewed the content of the article and removed a good portion of the text as it dealt with arthritis in general (which is already adequately covered in articles dedicated to the topic), however most of the content in the article still address the topic generally (the article also contained some blatant inaccuracies and poorly worded/written sections which I somewhat remedied). I actually somewhat regret my efforts, seeing that it might have been tantamount to putting lipstick on a pig, to put it harshly/bluntly.

I considered seconding LiamSP's proposal for merger. However, the slim portion of the content that is actually not already covered in respective dedicated articles on the general topic of arthritis, osteoarthritis etc. and/or that actually addresses the knee in particular is often unsourced. Sources cited are also often non-scientific. More generally, the page does not appear to meet Wikipedia:Notability standards. Hence, as I reckon there is hardly anything worth salvaging, the article should be binned outright. Even if the topic warrants its own article, it would be just as well to write it from scratch.

Kind regards, -J Jay Hodec (talk) 14:05, 20 December 2018 (UTC)Reply

  • Our editing policy is to improve articles rather than deleting them and starting again. The proposal has been terminated. Andrew D. (talk) 23:01, 22 December 2018 (UTC)Reply
True, however, as noted above, I find it questionable as to whether it makes sense to have a stand-alone article on this topic in any case (the last point I made was an off-handed remark, and not the central argument). Still, I'll attempt to clean up and improve the article for now. I'd still like to hear other contributors' opinions regarding a possible merger or deletion, though ... Sincerely, -J Jay Hodec (talk) 17:24, 23 December 2018 (UTC)Reply