Talk:Gramicidin

Latest comment: 14 years ago by Hbaryan in topic IT SHOULD BE 'CELL MEMBRANE'

Incorrect picture edit

The picture of Gramicidin A is incorrect (2 instead of 6 H-bonds between the monomers, and so on). How it has been generated? It should be replaced.Biophys 03:35, 31 October 2006 (UTC)Reply

It was created in ChemDraw. If you're so inclined to make another one, be my guest. But it depicts the motif quite well, IMHO Jgassens 21:17, 14 July 2007 (UTC)Reply
Well, the numbers of hydrogen bonds between the monomer and within each monomer are wrong (actually, there are more H-bonds). Do we need this picture when someone inserted a better and rotating one?Biophys 01:57, 5 September 2007 (UTC)Reply
I don't see why the picture has to rotate. And I don't know if it's a very good picture. Why is the molecule several times in there? This is just an artefact of the structure determination but it has no meaning for someone who tries to understand the structure. And why do you need to show the uncertainties? FelixP 16:58, 1 November 2007 (UTC)Reply


IT SHOULD BE 'CELL MEMBRANE' edit

The first line of para "Pharmacological effects" reads : 'Gramicidin's bactericidal activity is a result of increasing the permeability of the bacterial cell wall allowing inorganic monovalent cations' Is it cell wall or cell membrane? I think it has to be cell membrane. —Preceding unsigned comment added by Hbaryan (talkcontribs) 13:56, 1 April 2010 (UTC)Reply


References edit

The references were moved to a separate section.Biophys 03:35, 31 October 2006 (UTC)Reply

Assessment comment edit

The comment(s) below were originally left at Talk:Gramicidin/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

There is something wrong with the statement about chloride ion(Cl-), which like most anions has very little in the way of hydration. It is the positive ions that have strong interactions with water molecules. SO this cannot be the basis of the cation selectivity. More likely is the prescence of negative charges.97.113.105.147 (talk) 22:13, 22 September 2009 (UTC)Reply

Last edited at 22:13, 22 September 2009 (UTC). Substituted at 16:35, 29 April 2016 (UTC)