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WikiProject class rating
editThis article was automatically assessed because at least one WikiProject had rated the article as stub, and the rating on other projects was brought up to Stub class. BetacommandBot 07:53, 10 November 2007 (UTC)
Metabolism
editFrom what I have gleaned, the long duration is becauae of the high cLogP and metabolism is via N-dealkylation of the piperidine ring. I have readf about serious side-effects in primates so I would like to know if it's use as a potential medication is checked with a low oral dose before depot.... or someone is going to be seriously ill for a month. — Preceding unsigned comment added by 81.99.74.135 (talk) 15:27, 7 May 2017 (UTC)
Opioid Activity
editIf the 8 position has an α-methyl benzyl or 2-(2-thienyl)-benzyl group then it has sub-nanomole affinity for the NOP receptors. — Preceding unsigned comment added by 81.99.74.135 (talk) 13:37, 29 July 2017 (UTC)