Talk:Delphinium glaucum
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- Could someone please provide evidence with a reference for D. scopulorum being a synonym for D. glaucum? This has some consequences in fields other than botany.
Richard Mansk edit
the scientist who isolated DMT in 1901
Richard Helmuth Frederick Manske NASCITA 14 Set 1901 Berlin-Mitte, Mitte, Berlin, Germany MORTE 7 Set 1977 (75 anni) Guelph, Wellington County, Ontario, Canada SEPOLTURA Non-Cemetery Burial ID PAGINA COMMEMORATIVA 89667801 · Visualizza fonte
PAGINA COMMEMORATIVA FOTO 1 FIORI 2
The chemist, who in 1931 synthesized N,N-Dimethyltryptamine (DMT) the prototypical indolethylamine hallucinogen. At the time of his death in 1977 at the age of 76, he left a solid legacy of alkaloid chemistry and 160 publications.
In 1906 Manske immigrated with his family to Macklin, Saskatchewan. After studying at Queen's and the University of Manchester and spending 5 years in the US, he returned to Canada in 1931 to the National Research Council, Ottawa. Appointed director of Dominion Rubber Co (now UniRoyal) Research Laboratories at Guelph, Ontario, in 1943, he retired in 1966 and joined the University of Waterloo as adjunct professor of chemistry. His studies of the plant alkaloids span some 50 years and resulted in over 150 research publications and 17 volumes of a standard reference monograph. His other interests ranged from music, astronomy, bird-watching and Greek philosophy to the culinary arts. Elected to the RSC (1935), he was president (1964) and honorary fellow (1967) of the Chemical Institute of Canada and received its medal (1959) and the Morley Medal of the American Chemical Society (1972). Giancabot (talk) 23:43, 25 July 2020 (UTC)
The Alkaloids: Chemistry and Physiology Volume 17, 1979, Pages x-xiii Richard Helmuth Frederick Manske (1901–1977) Author links open overlay panelD.B.MacLean https://doi.org/10.1016/S1876-0813(08)60295-X Get rights and content Publisher Summary This chapter presents a brief biography of the author of this volume, Richard H. F. Manske. It mentions his various contributions to his field. Richard H. F. Manske was born in Germany in 1901 and came with his parents to Canada in 1906. He died in Guelph, Ontario in September 1977 from injuries sustained in an automobile accident early in the same year. As a graduate student at Manchester, Manske determined the structures of harmine and harmaline and synthesized both alkaloids. He also synthesized rutaecarpine, as he liked to recall, by accident. Another fortuitous experiment was his discovery of the use of hydrazine in the hydrolysis of phthalimides. He also collaborated at this time with A. Lapworth in one of the pioneering studies of physical organic chemistry. Besides his classic studies on the isoquinoline family of alkaloids, Manske also undertook, in collaboration with Leo Marion, an examination of the Lycopodiaceae native to Canada. From this work, some 30 alkaloids were characterized, and though he did not himself participate in a major way in their structural elucidation, he always followed the work with interest and insight.
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ScienceDirect ® is a registered trademark of Elsevier B.V. Giancabot (talk) 23:47, 25 July 2020 (UTC)
Chapter 1 R.H.F. Manske: Fifty Years of Alkaloid Chemistry Author links open overlay panelD.B.MacLeanV.Snieckus https://doi.org/10.1016/S1099-4831(08)60039-5 Get rights and content Giancabot (talk) 23:50, 25 July 2020 (UTC)
DMT was first synthesized in 1931 by Canadian chemist Richard Helmuth Fredrick Manske (1901–1977). Its discovery as a natural product is generally credited to Brazilian chemist and microbiologist Oswaldo Gonçalves de Lima (1908–1989) who, in 1946, isolated an alkaloid he named nigerina (nigerine) from the root bark of jurema preta, that is, Mimosa tenuiflora. However, in a careful review of the case Jonathan Ott shows that the empirical formula for nigerine determined by Gonçalves de Lima, which notably contains an atom of oxygen, can only match a partial, "impure" or "contaminated" form of DMT. It was only in 1959, when Gonçalves de Lima provided American chemists a sample of Mimosa tenuiflora roots, that DMT was unequivocally identified in this plant material. Less ambiguous is the case of isolation and formal identification of DMT in 1955 in seeds and pods of Anadenanthera peregrina by a team of American chemists led by Evan Horning (1916–1993). Since 1955 DMT has been found in a host of organisms: in at least 50 plant species belonging to 10 families, and in at least 4 animal species, including one gorgonian and 3 mammalian species (see Endogenous DMT). Giancabot (talk) 23:52, 25 July 2020 (UTC)