Talk:Calitoxin

GA Review

This review is transcluded from Talk:Calitoxin/GA1. The edit link for this section can be used to add comments to the review.

Reviewer: Sasata (talk · contribs) 02:27, 6 November 2014 (UTC)

Review coming soon. Sasata (talk) 02:27, 6 November 2014 (UTC)

Sorry for the delay ... here are some starter comments:

• the lead is not yet a good summary of the article (see WP:LEAD for guidelines)

how about now? —Gaff ^ταλκ 19:27, 19 November 2014 (UTC)

• possibly useful wikilinks: neurotransmitter release, neuromuscular junction, stinging cell, amino acid sequence, homologous, voltage-gated sodium channel; Glu and Lys should be spelled out

 Done —Gaff ^ταλκ 16:44, 18 November 2014 (UTC)

• ”Calitoxin is a highly potent neurotoxin, which can be found in the nematocysts, organelles in stinging cells, of the Calliactis parasitica.” fix grammar

better?? —Gaff ^ταλκ 16:54, 18 November 2014 (UTC)

• ”Two genes coding for two highly homologous calitoxins are discovered and analyzed” fix

—Gaff ^ταλκ 17:01, 18 November 2014 (UTC)

• missing information: who discovered calitoxin, when, and under what circumstances? The short etymology section could perhaps be merged with this info

renamed and expanded the section. Hopefully sufficient? —Gaff ^ταλκ 21:16, 18 November 2014 (UTC)

• has anyone quantified the amount of calitoxin in Calliactis parasitica?

Not that I can find. I found the minimum dose (it is in the article). The extraction method sounds pretty crude, so I doubt that anyone can say exactly how much is in there. —Gaff ^ταλκ 04:00, 19 November 2014 (UTC)

• ”by injecting a 0.1 mL solution with 0.2 µg lyophilized CLX of into the hemocoel.” this is far too much detail for a general encyclopedia

— fixed. —Gaff ^ταλκ 04:00, 19 November 2014 (UTC)

• what is the toxin's isoelectric point?

done. —Gaff ^ταλκ 17:22, 18 November 2014 (UTC)

• are there any disulfide bonds?

. There are three. Added. —Gaff ^ταλκ 17:09, 18 November 2014 (UTC)

• is the compound commonly used in studies of ion channels?

— fixed. —Gaff ^ταλκ 04:00, 19 November 2014 (UTC)

Comments

• @Sasata: The above concerns have been addressed. I've substantially expanded the article, added a table comparing the sequences, and restructured problematic sections. Please let me know what else can be done to bring this to GA status. —Gaff ^ταλκ 19:27, 19 November 2014 (UTC)

The corrections and additions look great! I've made some additional copyedits and added more links; feel free to revert if you don't like them. I'm confident that this article now meets the GA criteria, and am happy to promote at his time. Cheers, Sasata (talk) 19:53, 21 November 2014 (UTC)