Talk:Anti-Müllerian hormone
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Untitled edit
The section on ovarian reserve and AMH needs clarification. AMH is produced by primary follicles on up to the very early antral stage, i.e., just before cyclic recruitment, hence serum levels do not vary over a woman's menstrual cycle. Thus high levels can occur in PCOS and low levels in poor ovarian reserve. An antral follicle count (AFC) by ultrasound is unlikely to reveal much additional information as AFC correlates well with AMH. A high AMH level does not neccessarily mean better fertility as it may indicate PCOS or possibly ovarian cancer. In fact AMH may drop before antral follicle counts do showing that low AMH serum levels is an earlier marker of declining ovarian reserve than AFC.
Currently, AMH has been shown to be a circulating marker specifically for granulosa cell tumour (GCT). GCT constitutes 3% of all ovarian tumours. According to one study AMH is increased only in the serum from women with GCT.
See:
La Marca and Volpe, 2007, "The Anti-Mullerian hormone and ovarian cancer." Human Reproduction Upate 13(3):265-73. PubMed Index: 17213257.
Das M, DJ Gillott, E Saridogan and O Djahanbakhch, 2008. "Anti-Mullerian hormone is increased in follicular fluid from unstimulated ovaries in women with polycystic ovary syndrome." Human Reproduction. PubMed Index: 18550512. June 10, 2008 Epub ahead of print.
Wiki Education Foundation-supported course assignment edit
This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): AlexandriaLee.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 14:26, 16 January 2022 (UTC)
Addressing sections that need additions above edit
Hi, I am new to the page, as well as to Wikipedia editing. From the introduction above on certain sections, I'd like to try and work on expanding on the topic of AMH on ovarian reserve. I have found some papers to address the overall background of the protein and its role in selection and recruitment. I've cited them here. [1][2][3][4].And I'd also like to discuss a bit about AMH and its role in both PCOS and normal type women. If there is anything else that needs addressing, or if there is any guidance or corrections that you'd like to share, I am all ears. Thank you very much!AlexandriaLee (talk) 18:32, 4 May 2017 (UTC)
References
- ^ Willis, GW; Hajdu, SI (March 1973). "Histologically benign teratoid metastasis of testicular embryonal carcinoma: report of five cases". American journal of clinical pathology. 59 (3): 338–43. PMID 4687350.
- ^ GRYNNERUP, ANNA GARCIA-ALIX; LINDHARD, ANETTE; SØRENSEN, STEEN (November 2012). "The role of anti-Müllerian hormone in female fertility and infertility - an overview". Acta Obstetricia et Gynecologica Scandinavica. 91 (11): 1252–1260. doi:10.1111/j.1600-0412.2012.01471.x.
- ^ Broer, S. L.; Broekmans, F. J. M.; Laven, J. S. E.; Fauser, B. C. J. M. (12 May 2014). "Anti-Mullerian hormone: ovarian reserve testing and its potential clinical implications". Human Reproduction Update. 20 (5): 688–701. doi:10.1093/humupd/dmu020.
- ^ Garg, D; Tal, R (July 2016). "The role of AMH in the pathophysiology of polycystic ovarian syndrome". Reproductive biomedicine online. 33 (1): 15–28. PMID 27174394.
Predicting menopause edit
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Measurement - JCEM review edit
doi:10.1210/jc.2013-3476 JFW | T@lk 12:43, 7 March 2014 (UTC)
Contraception and AMH edit
February 2022
"Oral contraceptives (OCs) are commonly used methods of contraception that may impact ovarian function. Few studies have examined the association of these factors with antimüllerian hormone (AMH), a marker of ovarian aging.
We observed a significant, inverse association between duration of OC use and mean AMH levels (P for trend = 0.036)".
https://www.empr.com/home/news/oral-contraceptive-use-tied-to-marker-of-ovarian-function/
https://www.empr.com/tag/contraception/
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What about other hormonal contraceptives?
And other contraceptives, like https://en.wikipedia.org/wiki/Copper_IUDs?
--91.159.188.74 (talk) 08:50, 18 February 2022 (UTC)
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The article's tone is neutral. Source links work and are relevant to the subject.
- Pisawagner (talk) 17:46, 20 January 2024 (UTC)