Talk:Alcoholic hepatitis

Wiki Education Foundation-supported course assignment

This article was the subject of a Wiki Education Foundation-supported course assignment, between 7 January 2020 and 31 January 2020. Further details are available on the course page. Student editor(s): Asowers15. Peer reviewers: Mrwikimed.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 13:46, 16 January 2022 (UTC)

Resources

Some resources when this article becomes something more than a redirect:

• Glasgow discriminant.
• Maddrey's discriminant: DF = (patient's prothrombin time control) × 4.6 + (bilirubin (µmol/l)/17.1)). Anything over 32 is severe.
• Intensive management when severe

Some work to do. JFW | T@lk 19:25, 20 September 2006 (UTC)

Danish destruction

The Danish Cochrane group has again rubbished a treatment so commonly used in hepatology. This time it's steroids in alcholic hepatitis: http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2036.2008.03685.x JFW | T@lk 10:59, 25 March 2008 (UTC)

hello im looking for info on alcohlic hepititis —Preceding unsigned comment added by 24.164.3.147 (talk) 01:13, 2 June 2009 (UTC)

Excellent New NEJM Review article

From the 6/25/2009 NEJM: This should be incorporated into the article...I'll try to find some time:

http://content.nejm.org/cgi/content/short/360/26/2758 Wawot1 (talk) 02:57, 30 June 2009 (UTC)

Steroids work (again)

doi:10.1136/gut.2010.224097 - this is a meta-analysis that we probably ought to include. Not a word about pentoxyfylline of course. JFW | T@lk 12:43, 5 January 2011 (UTC)

The French have evaluated acetylcysteine + steroids vs steroids alone. It works on short-term mortality, but the series was too small to show a definite mortality benefit (although it was p=0.07, so who knows). doi:10.1056/NEJMoa1101214 JFW | T@lk 22:53, 12 November 2011 (UTC)

Liver transplantation is sometimes good as a rescue treatment, but there will be debate about suitability in people with a long history of alcoholicism. doi:10.1056/NEJMoa1105703. JFW | T@lk 22:54, 12 November 2011 (UTC)

Merging and/vcoordination with Steatohepatitis

Seems to be the same disease.--Kmhkmh (talk) 02:51, 18 June 2012 (UTC)

Meta-analysis

doi:10.1053/j.gastro.2015.06.006 - steroids and pentoxifylline with or without acetylcysteine. JFW | T@lk 15:06, 24 September 2015 (UTC)

Asowers15 (talk) 00:01, 9 January 2020 (UTC)

Wiki Medicine Project

Hello all, I am a 4th year medical student and I will be editing this page for a class. I have added a list below of a few things I am hoping to add/edit 1. The lead. I would like to clean this up and make it a bit more understandable (i.e. adding symptoms of hepatic encephalopathy) 2. Add a section discussing possible sequela of alcoholic hepatitis and expand on it (bleeding, etc.). 3. Expand on signs and symptoms, including possibly adding photos of some symptoms. 4. Expand on management, including discussion of liver transplantation. 5. Discuss short term prognosis vs long term (alcoholic hepatitis vs cirrhosis, and make those differences more clear for the non-medical professional).Asowers15 (talk) 00:01, 9 January 2020 (UTC)

Thanks. The content needs close review because it mixes up symptoms & blood test results. Also, steroids are very rarely used even in those with a high Maddrey because very limited evidence (e.g. STOPAH trial). JFW | T@lk 06:42, 24 January 2020 (UTC)

Peer Review for Alcoholic Hepatitis

-The lead is strong and concise.

-Signs and Symptoms section: second paragraph seems more relevant to the pathophysiology, perhaps consider moving it to that section. Also, clarification on final sentence about alcoholic steatonecrosis - it seems to be referring to the previous few sentences, but clarification would be helpful.

-The illustration for the Pathogenesis of alcoholic liver injury is relevant and detailed, and I believe that a written explanation would be helpful to clarify for many readers.

-I see links to modified Maddrey's discriminant function score, MELD score and Child-Pugh score - perhaps a brief description of these scoring systems can be added to this article

-Strong Management section

Overall, strong work! — Preceding unsigned comment added by Mrwikimed (talk • contribs) 16:16, 26 January 2020 (UTC)

Hey, Thanks for the feedback. I made several of the changes you suggested as I agree, I think it is much better for the article as a whole. Thank you for your help! Asowers15 (talk) 10:57, 31 January 2020 (UTC)