Talk:Adenocarcinoma in situ of the lung

Latest comment: 10 years ago by Patho in topic Removed > Pulmonary carcinoma

Association of Lung Cancer Variants with Smoking

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Hey TylerDurden8823:

Sorry to redact your statement that BAC and Carcinoids are the only variants of lung cancer not associated with smoking. Others off the top of my head include LELC, Mucoepidermoid carcinoma, adenoid cystic carcinoma, epithelial-myoepithelial carcinoma, pleuropulmonary blastomas, and some other non-carcinomatous variants.

Keep on working on the lung cancer articles, PLEASE - I need the excellent help :-)

Best regards:Cliff (a/k/a "Uploadvirus") (talk) 02:41, 29 April 2012 (UTC)Reply

Removed > Pulmonary carcinoma

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Gross pathology photograph from the lungs of a patient who died of widespread bilateral BAC. A cut surface of the formalin-inflated lungs shows multiple, small, gray-white nodules with absence of necrosis, hemorrhage, or architectural distortion. The bronchi course normally through the lung tissue, and the presence of air bronchograms radiographically in such cases is not surprising.

Lung cancers are an extremely heterogeneous family of malignant neoplasms,[1] with well over 50 different histological variants recognized under the 2004 revision of the World Health Organization ("WHO-2004") typing system, currently the most widely used lung cancer classification scheme.[2] Because these variants can have widely differing genetic, biological, and clinical properties, including response to treatment, correct classification of lung cancer cases are necessary to assure that lung cancer patients receive optimum management.[3][4]

Approximately 98% of lung cancers are carcinoma, which are tumors composed of cells with epithelial characteristics.[5] 8 major groups of lung carcinomas are recognized in WHO-2004:[2]

  • Squamous Cell Carcinoma
  • Small Cell Carcinoma
  • Adenocarcinoma
  • Large Cell Carcinoma
  • Adenosquamous Carcinoma
  • Sarcomatoid Carcinoma
  • Carcinoid Tumor
  • Salivary Gland-like Carcinoma

patho (talk) 14:40, 14 February 2014 (UTC)Reply

References

  1. ^ Roggli VL, Vollmer RT, Greenberg SD, McGavran MH, Spjut HJ, Yesner R (June 1985). "Lung cancer heterogeneity: a blinded and randomized study of 100 consecutive cases". Hum. Pathol. 16 (6): 569–79. doi:10.1016/S0046-8177(85)80106-4. PMID 2987102.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ a b Travis, William D; Brambilla, Elisabeth; Muller-Hermelink, H Konrad; Harris, Curtis C, eds. (2004). Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart (PDF). World Health Organization Classification of Tumours. Lyon: IARC Press. ISBN 92-832-2418-3. Retrieved 27 March 2010.
  3. ^ Rossi G, Marchioni A, Sartori1 G, Longo L, Piccinini S, Cavazza A (2007). "Histotype in non-small cell lung cancer therapy and staging: The emerging role of an old and underrated factor". Curr Resp Med Rev. 3: 69–77. doi:10.2174/157339807779941820.{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: numeric names: authors list (link)
  4. ^ Vincent MD (August 2009). "Optimizing the management of advanced non-small-cell lung cancer: a personal view". Curr Oncol. 16 (4): 9–21. doi:10.3747/co.v16i4.465. PMC 2722061. PMID 19672420.
  5. ^ Travis WD, Travis LB, Devesa SS (January 1995). "Lung cancer". Cancer. 75 (1 Suppl): 191–202. doi:10.1002/1097-0142(19950101)75:1+<191::AID-CNCR2820751307>3.0.CO;2-Y. PMID 8000996.{{cite journal}}: CS1 maint: multiple names: authors list (link)