Talk:5-HT2 receptor

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Latest comment: 15 years ago1 comment1 person in discussion

How can agomelatine be listed as both an agonist and an antagonist?

That must be an error? I am not a biochemist but one reference (M. J. Millan, A. Gobert, F. Lejeune, A. Dekeyne, A. Newman-Tancredi, V. Pasteau, J.-M. Rivet & D. Cussac (2003). "The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways". The Journal of pharmacology and experimental therapeutics. 306 (3): 954–954. doi:10.1124/jpet.103.051797. PMID 12750432. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)) calls it a melatonin agonist and a 2C antagonist, so I have erased agomelatine from the list of agonists. — fnielsen (talk) 10:02, 9 October 2008 (UTC)Reply

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