TTLL3

TTLL3
Identifiers
Aliases	TTLL3, HOTTL, tubulin tyrosine ligase like 3
External IDs	MGI: 2141418 HomoloGene: 134361 GeneCards: TTLL3
Gene location (Human)
Chr.	Chromosome 3 (human)
End	9,855,138 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	113,391,548 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; canal of the cervix; ; sural nerve; ; left uterine tube; ; gastric mucosa; ; anterior pituitary; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; gallbladder; ; right coronary artery;
	Top expressed in
	spermatid; ; utricle; ; seminiferous tubule; ; cerebellar cortex; ; olfactory epithelium; ; spermatocyte; ; visual cortex; ; thymus; ; yolk sac; ; superior frontal gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	ATP binding; protein-glycine ligase activity, initiating; nucleotide binding; ligase activity; protein-glycine ligase activity;
Cellular component	microtubule; axoneme; microtubule cytoskeleton; cytoplasm; cell projection; cilium; cytoskeleton; cytosol;
Biological process	axoneme assembly; cilium assembly; protein polyglycylation;
	Sources:Amigo / QuickGO
Orthologs
	26140
	101100
	ENSG00000214021
	ENSMUSG00000030276
	Q9Y4R7
	A4Q9E5
	NM_001025930; NM_015644; NM_001366051
	NM_001142732; NM_133923
	NP_001021100; NP_001352980
	NP_001136204; NP_598684
	Wikidata
View/Edit Human	View/Edit Mouse

Tubulin tyrosine ligase-like family, member 3 is a protein that in humans is encoded by the TTLL3 gene.^[5]

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000214021 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030276 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Tubulin tyrosine ligase-like family, member 3". Retrieved 2011-09-21.

Trichet V, Ruault M, Roizès G, De Sario A (October 2000). "Characterization of the human tubulin tyrosine ligase-like 1 gene (TTLL1) mapping to 22q13.1". Gene. 257 (1): 109–117. doi:10.1016/S0378-1119(00)00383-8. PMID 11054573.
Rogowski K, Juge F, van Dijk J, Wloga D, Strub JM, Levilliers N, et al. (June 2009). "Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation". Cell. 137 (6): 1076–1087. doi:10.1016/j.cell.2009.05.020. PMID 19524510. S2CID 953190.

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