TRNA1Val (adenine37-N6)-methyltransferase

TRNA1Val (adenine37-N6)-methyltransferase (EC 2.1.1.223, YfiC) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA1Val (adenine37-N6)-methyltransferase.[1] This enzyme catalyses the following chemical reaction

TRNA1Val (adenine37-N6)-methyltransferase
Identifiers
EC no.2.1.1.223
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
S-adenosyl-L-methionine + adenine37 in tRNA1Val S-adenosyl-L-homocysteine + N6-methyladenine37 in tRNA1Val

The enzyme specifically methylates adenine37 in tRNA1Val (anticodon cmo5UAC).

References

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  1. ^ Golovina AY, Sergiev PV, Golovin AV, Serebryakova MV, Demina I, Govorun VM, Dontsova OA (June 2009). "The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC)". RNA. 15 (6): 1134–41. doi:10.1261/rna.1494409. PMC 2685529. PMID 19383770.
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