Tripartite motif-containing protein 16 is a protein that in humans is encoded by the TRIM16 gene .[ 4] [ 5]
This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family.
The proteins of this family have been reported to be involved in a variety of biological processes including cell growth , differentiation and pathogenesis . Expression of this gene was detected in most tissues. Its function, however, has not yet been determined.[ 5]
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047821 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (May 2001). "The tripartite motif family identifies cell compartments" . EMBO J . 20 (9): 2140–51. doi :10.1093/emboj/20.9.2140 . PMC 125245 . PMID 11331580 .
^ a b "Entrez Gene: TRIM16 tripartite motif-containing 16" .
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Cheung BB, Bell J, Raif A, et al. (2006). "The estrogen-responsive B box protein is a novel regulator of the retinoid signal" . J. Biol. Chem . 281 (26): 18246–56. doi :10.1074/jbc.M600879200 . PMID 16636064 .