The mixed 4 × 100 metre freestyle relay event at the 2010 Youth Olympic Games took place on August 15, at the Singapore Sports School.
Medalists edit
| Gold |  China |
3:31.34 |
| Silver |  Australia |
3:31.69 |
| Bronze |  France |
3:35.90 |
Heats edit
Heat 1 edit
| Rank | Lane | Nationality | Time | Notes |
|---|---|---|---|---|
| 1 | 5 | China
|
3:39.39 | Q |
| 2 | 4 |  Hong Kong
|
3:40.34 | Q |
| 3 | 6 |  Serbia
|
3:41.15 | |
| 4 | 3 |  Italy
|
3:42.44 | |
| - | 2 |  Spain
|
- | DSQ |
Heat 2 edit
| Rank | Lane | Nationality | Time | Notes |
|---|---|---|---|---|
| 1 | 5 |  Canada
|
3:36.80 | Q |
| 2 | 4 | France
|
3:37.03 | Q |
| 3 | 7 |  United States
|
3:38.89 | Q |
| 4 | 6 |  Russia
|
3:39.69 | Q |
| 5 | 2 |  South Africa
|
3:43.85 | |
| 6 | 3 |  Iceland
|
3:49.60 |
Heat 3 edit
| Rank | Lane | Nationality | Time | Notes |
|---|---|---|---|---|
| 1 | 4 | Australia
|
3:34.67 | Q |
| 2 | 3 |  Germany
|
3:38.69 | Q |
| 3 | 5 |  Brazil
|
3:41.07 | |
| 4 | 2 |  Singapore
|
3:42.88 | |
| 5 | 6 |  Japan
|
3:49.23 | |
| 6 | 7 |  Trinidad and Tobago
|
3:51.35 |
Final edit
| Rank | Lane | Nationality | Time | Notes |
|---|---|---|---|---|
|
7 | China
|
3:31.34 | |
|
4 | Australia
|
3:31.69 | |
|
3 | France
|
3:35.90 | |
| 4 | 5 | Canada
|
3:36.05 | |
| 5 | 6 | Germany
|
3:36.06 | |
| 6 | 2 | United States
|
3:39.08 | |
| 7 | 8 | Hong Kong
|
3:40.08 | |
| 8 | 1 | Russia
|
3:42.63 |