Suzanne Ruth Pfeffer is an American neuroscientist who is a professor at Stanford University.[2] Her research investigates the molecular mechanisms that cause receptors to be transported between membrane compartments in cells, and she is an expert in Rab GTPases[3][4][5] and the molecular basis of inherited Parkinson's disease.[1] She is a Fellow of the American Association for the Advancement of Science, American Academy of Arts and Sciences and the American Society for Cell Biology.[6]
Suzanne Pfeffer | |
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![]() Pfeffer in 2010 | |
Born | Suzanne Ruth Pfeffer |
Alma mater | University of California, Berkeley (BS) University of California, San Francisco (PhD) |
Scientific career | |
Fields | Parkinson's disease[1] |
Institutions | Stanford University |
Thesis | The role of coated vesicles in intracellular transport (1983) |
Website | profiles |
Early life and education
editPfeffer has said that she became interested in human physiology as a child. She was an undergraduate student at the University of California, Berkeley, where she became interested in biochemistry.[7] She worked with Michael Chamberlin on binding of Escherichia coli polymerase to T7 DNA polymerase.[8] She moved to the University of California, San Francisco for her graduate studies, where she worked with Regis B. Kelly on synaptic vessels.[7] Her doctoral research investigated the role of coated vesicles in intracellular transport.[9]
Research and career
editAfter her PhD, she moved to Stanford University as a Hay Whitney postdoctoral fellow, where she worked with James Rothman on Golgi transport.[7][10]
Pfeffer set up her own research program at Stanford University, where she was the first woman to be appointed to the department of biochemistry.[7] Her research investigates the fundamental mechanisms of membrane trafficking.[7][11]
Selected publications
edit- Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi[3]
- "Rab9 functions in transport between late endosomes and the trans Golgi network[4]
- Rab GTPases: specifying and deciphering organelle identity and function[5]
Awards and honors
edit- 1992 Elected Fellow of the American Association for the Advancement of Science[12]
- 2003 President of the American Society for Cell Biology[13]
- 2010 President of the American Society for Biochemistry and Molecular Biology[14]
- 2013 Elected to the American Academy of Arts and Sciences[15]
- 2017 Elected Fellow of the American Society for Cell Biology[16]
- 2024 Elected member of the National Academy of Sciences[17]
References
edit- ^ a b Suzanne Pfeffer publications indexed by Google Scholar
- ^ Suzanne Pfeffer publications from Europe PubMed Central
- ^ a b Suzanne R. Pfeffer; James E. Rothman (1 January 1987). "Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi". Annual Review of Biochemistry. 56: 829–852. doi:10.1146/ANNUREV.BI.56.070187.004145. ISSN 0066-4154. PMID 3304148. Wikidata Q39664981.
- ^ a b D Lombardi; Thierry Soldati; M A Riederer; Y Goda; M Zerial; S R Pfeffer (1 February 1993). "Rab9 functions in transport between late endosomes and the trans Golgi network". The EMBO Journal. 12 (2): 677–682. doi:10.1002/J.1460-2075.1993.TB05701.X. ISSN 0261-4189. PMC 413253. PMID 8440258. Wikidata Q28609814.
- ^ a b Pfeffer SR (December 2001). "Rab GTPases: specifying and deciphering organelle identity and function". Trends in Cell Biology. 11 (12): 487–91. doi:10.1016/S0962-8924(01)02147-X. ISSN 0962-8924. PMID 11719054. Wikidata Q29620750.
- ^ profiles
.stanford .edu /suzanne-pfeffer - ^ a b c d e Sedwick, Caitlin (2009-04-06). "Suzanne Pfeffer: Sorting through membrane trafficking". Journal of Cell Biology. 185 (1): 4–5. doi:10.1083/jcb.1851pi. ISSN 1540-8140. PMC 2700508. PMID 19349576.
- ^ Pfeffer, S. R.; Stahl, S. J.; Chamberlin, M. J. (1977-08-10). "Binding of Escherichia coli RNA polymerase to T7 DNA. Displacement of holoenzyme from promoter complexes by heparin". The Journal of Biological Chemistry. 252 (15): 5403–5407. ISSN 0021-9258. PMID 328501.
- ^ Pfeffer, Suzanne Ruth. The role of coated vesicles in intracellular transport. escholarship.org (PhD thesis). OCLC 1020060429. ProQuest 303125660.
- ^ "Suzanne R. Pfeffer, PhD | Parkinson's Disease". michaeljfox.org. Retrieved 2023-07-23.
- ^ Pfeffer, Suzanne; Aivazian, Dikran (2004). "Targeting Rab GTPases to distinct membrane compartments". Nature Reviews Molecular Cell Biology. 5: 886–896.
- ^ "Inside AAAS". www.science.org. Science. 2023-07-23. Retrieved 2024-05-28.
- ^ "ASCB Presidents". ascb.org. Retrieved 2023-07-23.
- ^ "Past presidents". asbmb.org. Retrieved 2023-07-23.
- ^ "Suzanne Pfeffer". amacad.org. American Academy of Arts & Sciences. 2023-07-23. Retrieved 2023-07-23.
- ^ "Suzanne Pfeffer - ASCB". ascb.org. The American Society for Cell Biology. 2024-05-28. Retrieved 2024-05-28.
- ^ "National Academy of Sciences Elects Members and International Members". www.nasonline.org. 30 April 2024. Retrieved 12 May 2024.