Sch 642305 is a chemical compound isolated from Penicillium verrucosum that inhibits bacterial DNA primase.[1]
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Names | |
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Preferred IUPAC name
(4S,8aR,12S,12aR)-12-Hydroxy-4-methyl-4,5,6,7,8,8a,12,12a-octahydro-2H-3-benzoxecine-2,9(1H)-dione | |
Identifiers | |
3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C14H20O4 | |
Molar mass | 252.310 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
edit- ^ Chu, Min; Mierzwa, Ronald; Xu, Ling; He, Ling; Terracciano, Joseph; Patel, Mahesh; Gullo, Vincent; Black, Todd; Zhao, Wenjun; Chan, Tze-Ming; McPhail, Andrew T (2003). "Isolation and Structure Elucidation of Sch 642305, a Novel Bacterial DNA Primase Inhibitor Produced by Penicilliumverrucosum". Journal of Natural Products. 66 (12): 1527–30. doi:10.1021/np0302302. PMID 14695789.