Sarah Luse (December 12, 1918 – December 28, 1970) was an American physician who was a professor of anatomy at Columbia University. Her research considered the development of imaging techniques to better understand the nervous system, with a focus on electron microscopy.

Sarah Luse
Born(1918-12-12)December 12, 1918
DiedDecember 28, 1970(1970-12-28) (aged 52)
Alma materRockford College
Case Western Reserve University
Scientific career
InstitutionsWashington University School of Medicine
Columbia University
Johns Hopkins University
Mayo Graduate School

Early life and education

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Luse was born in Emmetsburg, Iowa.[1] She grew up working on a farm, where she was responsible for looking after animals and operating farm machinery.[2] She attended Rockford College and graduated in 1940.[3] After graduating, she worked as a technician in Mayo Clinic Hospital, Rochester.[4] She was responsible for interpreting electroencephalograms. In 1945, she moved to Case Western Reserve University, where she oversaw electroencephalography. She was awarded the George W. Crile scholarship and made a doctor of medicine in 1949. Luse interned in Johns Hopkins University, and returned to Ohio as a medical resident. She held a residency at the Mayo Graduate School, and, in 1953, was made first assistant in neuropathology.[1]

Research and career

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Luse joined the Washington University School of Medicine as an American Cancer Society Fellow. She held various positions, including being Professor of Pathology.[citation needed] In 1964 she was made Head of the Department of Anatomy, and was the first women to hold such a position.[3] She moved to Columbia University as Professor of Anatomy in 1967.[1][5]

Luse's research made use of electron microscopy to better understand the nervous system.[3][6][7] She studied tumors in the adrenal cortex, diseases that cause demyelination and the processes which result in the formation of myelin.[1] She showed that multiple sclerosis causes damage on neurons.[1][5]

In 1959, Luse joined the Armed Forces Institute of Pathology,[1][2] where she applied electroencephalography to understand the impact of barometric pressures in aviation medicine.[4]

Selected publications

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  • LUSE SA (September 1, 1956). "Electron microscopic observations of the central nervous system". Journal of Biophysical and Biochemical Cytology. 2 (5): 531–542. ISSN 0095-9901. PMC 2223987. PMID 13376632. Wikidata Q36422869.
  • S A LUSE (November 1, 1956). "Formation of myelin in the central nervous system of mice and rats, as studied with the electron microscope". Journal of Biophysical and Biochemical Cytology. 2 (6): 777–784. doi:10.1083/JCB.2.6.777. ISSN 0095-9901. PMC 2224009. PMID 13398444. Wikidata Q30811805.
  • L W O'Neal; D M Kipnis; S A Luse; P E Lacy; L Jarett (June 1, 1968). "Secretion of various endocrine substances by ACTH-secreting tumors--gastrin, melanotropin, norepinephrine, serotonin, parathormone, vasopressin, glucagon". Cancer. 21 (6): 1219–1232. doi:10.1002/1097-0142(196806)21:6<1219::AID-CNCR2820210625>3.0.CO;2-M. ISSN 0008-543X. PMID 4296748. Wikidata Q68576941.

Personal life

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In 1970, Luse died unexpectedly of myocarditis in a hotel in San Francisco.[1]

References

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  1. ^ a b c d e f g Eckman, James (April 1, 1971). "Sarah Amanda Luse 1918–1970". Neurology. 21 (4): 391. doi:10.1212/WNL.21.4.391. ISSN 0028-3878. PMID 4928761. S2CID 6007237.
  2. ^ a b "Missouri Women in the Health Sciences - Biographies - Sarah A. Luse". beckerexhibits.wustl.edu. Retrieved December 27, 2022.
  3. ^ a b c "Sarah Amanda Luse". Neuroscience. Retrieved December 27, 2022.
  4. ^ a b "Women's History Month" (PDF). 2020.
  5. ^ a b "DR. SARAH A. LUSE, A PATHOLOGIST, 52". The New York Times. January 2, 1971. ISSN 0362-4331. Retrieved December 27, 2022.
  6. ^ "Sarah Luse - We've Come a Long Way, Maybe". beckerexhibits.wustl.edu. Retrieved December 27, 2022.
  7. ^ Pappas, George D. (July 1, 1963). "Ultrastructure and Metabolism of the Nervous System: Research Publications of the Association for Research in Nervous and Mental Disease". Archives of Neurology. 9 (1): 103. doi:10.1001/archneur.1963.00460070113015. ISSN 0003-9942.