Santacruz (Spanish pronunciation: [santaˈkɾus]) is a town and municipality in the Nariño Department, Colombia.

Santacruz
Municipality and town
Flag of Santacruz
Location of the municipality and town of Santacruz in the Nariño Department of Colombia
Location of the municipality and town of Santacruz in the Nariño Department of Colombia
Coordinates: 1°13′19″N 77°40′38″W / 1.22194°N 77.67722°W / 1.22194; -77.67722
Country Colombia
DepartmentNariño Department
Time zoneUTC-5 (Colombia Standard Time)