SPIKE (Signaling Pathways Integrated Knowledge Engine) is a database of highly curated interactions for particular human pathways.[1]

SPIKE
Content
Descriptionhighly curated human signaling pathways.
OrganismsHomo sapiens
Contact
Research centerSackler School of Medicine, Tel Aviv University, Israel.
LaboratoryDepartment of Human Molecular Genetics and Biochemistry,
AuthorsArnon Paz
Primary citationPaz & al. (2011)[1]
Release date2010
Access
Websitehttp://www.cs.tau.ac.il/~spike/
Download URLhttp://www.cs.tau.ac.il/~spike/formats.html

Development

edit

SPIKE was developed by Ron Shamir's computational biology group in cooperation with the group of Yosef Shiloh, an Israel Prize recipient for his research in systems biology, and the group of Karen Avraham, a leading researcher of human deafness, all from Tel Aviv University.

See also

edit

References

edit
  1. ^ a b Paz, Arnon; Brownstein Zippora; Ber Yaara; Bialik Shani; David Eyal; Sagir Dorit; Ulitsky Igor; Elkon Ran; Kimchi Adi; Avraham Karen B; Shiloh Yosef; Shamir Ron (Jan 2011). "SPIKE: a database of highly curated human signaling pathways". Nucleic Acids Res. 39 (Database issue). England: D793-9. doi:10.1093/nar/gkq1167. PMC 3014840. PMID 21097778.
edit