Sorting nexin-18 is a protein that in humans is encoded by the SNX18 gene.[5][6][7]

SNX18
Identifiers
AliasesSNX18, SH3PX2, SH3PXD3B, SNAG1, sorting nexin 18
External IDsMGI: 2137642; HomoloGene: 14164; GeneCards: SNX18; OMA:SNX18 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_052870
NM_001102575
NM_001145427

NM_130796

RefSeq (protein)

NP_001096045
NP_001138899
NP_443102

NP_570614

Location (UCSC)Chr 5: 54.52 – 54.55 MbChr 13: 113.73 – 113.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. The specific function of this protein has not been determined.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000178996Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042364Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Seet LF, Hong W (Sep 2006). "The Phox (PX) domain proteins and membrane traffic". Biochim Biophys Acta. 1761 (8): 878–96. doi:10.1016/j.bbalip.2006.04.011. PMID 16782399.
  6. ^ Thornhill PB, Cohn JB, Drury G, Stanford WL, Bernstein A, Desbarats J (Sep 2007). "A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells". FEBS Lett. 581 (23): 4455–62. doi:10.1016/j.febslet.2007.08.025. PMID 17761170. S2CID 23223511.
  7. ^ a b "Entrez Gene: SNAG1 sorting nexin associated golgi protein 1".

Further reading

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