Protein shroom3 also known as shroom-related protein is a protein that in humans is encoded by the SHROOM3 gene .[5] [6] [7]
Protein shroom3 is a PDZ domain -containing protein that belongs to a family of Shroom-related proteins . This protein may be involved in regulating cell shape in certain tissues.
Clinical relevance
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References
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^ a b c GRCh38: Ensembl release 89: ENSG00000138771 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029381 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ a b Hildebrand JD, Soriano P (1999). "Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice" . Cell . 99 (5): 485–97. doi :10.1016/S0092-8674(00)81537-8 PMID 10589677 . S2CID 17185521 . ^ Hagens O, Ballabio A, Kalscheuer V, Kraehenbuhl JP, Schiaffino MV, Smith P, Staub O, Hildebrand J, Wallingford JB (2006). "A new standard nomenclature for proteins related to Apx and Shroom" . BMC Cell Biol . 7 (1): 18. doi :10.1186/1471-2121-7-18 PMC 1481537 PMID 16615870 . ^ a b "Entrez Gene: SHROOM3 shroom family member 3" .^ Tariq M, Belmont JW, Lalani S, Smolarek T, Ware SM (2011). "SHROOM3 is a novel candidate for heterotaxy identified by whole exome sequencing" . Genome Biol . 12 (9): R91. doi :10.1186/gb-2011-12-9-r91 PMC 3308054 PMID 21936905 . ^ Plageman TF, Chung MI, Lou M, Smith AN, Hildebrand JD, Wallingford JB, Lang RA (2010). "Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination" . Development . 137 (3): 405–15. doi :10.1242/dev.045369 . PMC 2858910 PMID 20081189 . ^ Grosse AS, Pressprich MF, Curley LB, Hamilton KL, Margolis B, Hildebrand JD, Gumucio DL (2011). "Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis" . Development . 138 (20): 4423–32. doi :10.1242/dev.065789 . PMC 3177312 PMID 21880782 . ^ Plageman TF, Zacharias AL, Gage PJ, Lang RA (2011). "Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis" . Developmental Biology . 357 (1): 227–34. doi :10.1016/j.ydbio.2011.06.027 . PMC 3619216 PMID 21726547 .
Further reading
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Juriloff DM, Harris MJ (2000). "Mouse models for neural tube closure defects" . Hum. Mol. Genet . 9 (6): 993–1000. doi :10.1093/hmg/9.6.993 PMID 10767323 . Benzinger A, Muster N, Koch HB, Yates JR, Hermeking H (2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer" . Mol. Cell. Proteomics . 4 (6): 785–95. doi :10.1074/mcp.M500021-MCP200 PMID 15778465 . Navarro-Lérida I, Martínez Moreno M, Roncal F, Gavilanes F, Albar JP, Rodríguez-Crespo I (2004). "Proteomic identification of brain proteins that interact with dynein light chain LC8". Proteomics . 4 (2): 339–46. doi :10.1002/pmic.200300528 . PMID 14760703 . S2CID 8868600 . Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 7 (2): 143–50. doi :10.1093/dnares/7.2.143 PMID 10819331 . Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence" . Genome Res . 8 (11): 1097–108. doi :10.1101/gr.8.11.1097 PMID 9847074 .
This article incorporates text from the United States National Library of Medicine , which is in the public domain .
