Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene.[5][6]

SH3GL2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSH3GL2, CNSA2, EEN-B1, SH3D2A, SH3P4, SH3 domain containing GRB2 like 2, endophilin A1
External IDsOMIM: 604465; MGI: 700009; HomoloGene: 20652; GeneCards: SH3GL2; OMA:SH3GL2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003026

NM_019535

RefSeq (protein)

NP_003017

NP_062408

Location (UCSC)Chr 9: 17.58 – 17.8 MbChr 4: 85.12 – 85.56 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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SH3GL2 has been shown to interact with DNM1,[7][8] Amphiphysin,[7][8] ADAM9,[9] SH3KBP1[10] and ADAM15.[9]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000107295Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028488Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Giachino C; Lantelme E; Lanzetti L; Saccone S; Bella Valle G; Migone N (Jul 1997). "A novel SH3-containing human gene family preferentially expressed in the central nervous system". Genomics. 41 (3): 427–34. doi:10.1006/geno.1997.4645. PMID 9169142.
  6. ^ "Entrez Gene: SH3GL2 SH3-domain GRB2-like 2".
  7. ^ a b Micheva, K D; Kay B K; McPherson P S (Oct 1997). "Synaptojanin forms two separate complexes in the nerve terminal. Interactions with endophilin and amphiphysin". J. Biol. Chem. 272 (43). UNITED STATES: 27239–45. doi:10.1074/jbc.272.43.27239. ISSN 0021-9258. PMID 9341169.
  8. ^ a b Modregger, Jan; Schmidt Anne A; Ritter Brigitte; Huttner Wieland B; Plomann Markus (Feb 2003). "Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1". J. Biol. Chem. 278 (6). United States: 4160–7. doi:10.1074/jbc.M208568200. ISSN 0021-9258. PMID 12456676.
  9. ^ a b Howard, L; Nelson K K; Maciewicz R A; Blobel C P (Oct 1999). "Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1". J. Biol. Chem. 274 (44). UNITED STATES: 31693–9. doi:10.1074/jbc.274.44.31693. ISSN 0021-9258. PMID 10531379.
  10. ^ Soubeyran, Philippe; Kowanetz Katarzyna; Szymkiewicz Iwona; Langdon Wallace Y; Dikic Ivan (Mar 2002). "Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors". Nature. 416 (6877). England: 183–7. Bibcode:2002Natur.416..183S. doi:10.1038/416183a. ISSN 0028-0836. PMID 11894095. S2CID 635702.

Further reading

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