In molecular biology, the restriction endonuclease BsobI/AvaI family of enzymes includes the AvaI and BsoBI restriction endonucleases from Anabaena variabilis and Bacillus stearothermophilus, both of which recognise the double-stranded sequence CYCGRG (where Y = T/C, and R = A/G) and cleave after C-1.[1]
| Endonuc-BsobI | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 restriction enzyme bsobi/dna complex structure: encirclement of the dna and histidine-catalyzed hydrolysis within a canonical restriction enzyme fold | |||||||||
| Identifiers | |||||||||
| Symbol | Endonuc-BsobI | ||||||||
| Pfam | PF09194 | ||||||||
| InterPro | IPR015277 | ||||||||
| SCOP2 | 1dc1 / SCOPe / SUPFAM | ||||||||
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References
edit- ^ van der Woerd MJ, Pelletier JJ, Xu S, Friedman AM (February 2001). "Restriction enzyme BsoBI-DNA complex: a tunnel for recognition of degenerate DNA sequences and potential histidine catalysis". Structure. 9 (2): 133–44. doi:10.1016/S0969-2126(01)00564-0. PMID 11250198.