RAP1 GTPase activating protein 2 is a protein in humans that is encoded by the RAP1GAP2 gene.[5]

RAP1GAP2
Identifiers
AliasesRAP1GAP2, GARNL4, RAP1GA3, RAP1 GTPase activating protein 2
External IDsMGI: 3028623; HomoloGene: 56695; GeneCards: RAP1GAP2; OMA:RAP1GAP2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001100398
NM_015085
NM_001330058

NM_001015046
NM_001364131
NM_001364132

RefSeq (protein)

NP_001093868
NP_001316987
NP_055900

NP_001015046
NP_001351060
NP_001351061
NP_001388587

Location (UCSC)Chr 17: 2.76 – 3.04 MbChr 11: 74.27 – 74.5 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a GTPase-activating protein that activates the small guanine-nucleotide-binding protein Rap1 in platelets. The protein interacts with synaptotagmin-like protein 1 and Rab27 and regulates secretion of dense granules from platelets at sites of endothelial damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000132359Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038807Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: RAP1 GTPase activating protein 2".

Further reading

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