Protein DEPP also known as decidual protein induced by progesterone (DEPP) and fasting-induced gene protein (FIG) is a protein that in humans is encoded by the DEPP gene.[5]

DEPP1
Identifiers
AliasesDEPP1, DEPP, FIG, Fseg, chromosome 10 open reading frame 10, autophagy regulator, C10orf10, DEPP1 autophagy regulator
External IDsOMIM: 611309; MGI: 1918730; HomoloGene: 48491; GeneCards: DEPP1; OMA:DEPP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007021

NM_001166580
NM_145980

RefSeq (protein)

NP_008952

NP_001160052
NP_666092

Location (UCSC)Chr 10: 44.97 – 44.98 MbChr 6: 116.63 – 116.63 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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The expression of this gene is induced by fasting as well as by progesterone. The protein encoded by this gene contains a t-synaptosome-associated protein receptor (SNARE) coiled-coil homology domain and a peroxisomal targeting signal. Production of the encoded protein leads to phosphorylation and activation of the transcription factor ELK1.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000165507Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048489Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: C10orf10 chromosome 10 open reading frame 10".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.