Portal:Medicine/Selected article/39, 2006

Tourette syndrome is an inherited neurological disorder with onset in childhood, characterized by the presence of multiple physical (motor) tics and at least one vocal (phonic) tic; these tics usually wax and wane. Tourette's is defined as part of a spectrum of tic disorders, which includes transient and chronic tics.

Tourette's was once considered a rare and bizarre syndrome, most often associated with the exclamation of obscene words or socially inappropriate and derogatory remarks (coprolalia). However, this symptom is present in fewer than 15% of people with Tourette's. It is no longer considered a rare condition, but it may not always be correctly identified because of the wide range of severity, with most cases classified as mild. Genetic and environmental factors each play a role in the etiology of Tourette's, but the exact causes are unknown. (More...)