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Sergei Nikolaievich Winogradsky (September 14, 1856 – February 25, 1953) (or Vinogradskyi) was a Ukrainian-Russian microbiologist, ecologist and soil scientist who pioneered the cycle of life concept. He discovered the first known form of lithotrophy during his research with Beggiatoa in 1887. He reported in Winogradsky S (1887). "Über Schwefelbakterien". Bot. Zeitung (45): 489–610. that Beggiatoa oxidized hydrogen sulfide (H2S) as an energy source and formed intracellular sulfur droplets. This research provided the first example of lithotrophy, but not autotrophy. His research on nitrifying bacteria would report the first known form of chemoautotrophy, showing how a lithotroph fixes carbon dioxide (CO2) to make organic compounds.

Winogradsky is best known for discovering chemoautotrophy, which soon became popularly known as chemosynthesis, the process by which organisms derive energy from a number of different inorganic compounds and obtain carbon in the form of carbon dioxide. (Full article...)