Plácido de Castro may refer to:
- José Plácido de Castro (1873–1908), Brazilian soldier and politician who led the revolt by which Acre became a state of Brazil
- Plácido de Castro, Acre, municipality in Acre, Brazil
- Plácido de Castro Futebol Club, football club in Acre, Brazil
This disambiguation page lists articles associated with the title Plácido de Castro.
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