Partial cleavage stimulation factor domain

The partial cleavage stimulation factor domain, or partial CstF domain, is a protein domain that occurs in proteins from apicomplexan parasites.[1]

Partial cleavage stimulation factor domain
Identifiers
Symbolpartial_CstF
PfamPF15861
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

Currently (as of 2012), little is known about the function of this domain. However, it is homologous to the amino-terminal part of the cleavage stimulation factor, which is thought to be involved with mRNA maturation in mammals. Proteins with this domain have been detected in the malaria parasite Plasmodium falciparum nucleus.[1]

References

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  1. ^ a b Oehring SC, Woodcroft BJ, Moes S, Wetzel J, Dietz O, Pulfer A, Dekiwadia C, Maeser P, Flueck C, Witmer K, Brancucci NM, Niederwieser I, Jenoe P, Ralph SA, Voss TS (November 2012). "Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum". Genome Biology. 13 (11): R108. doi:10.1186/gb-2012-13-11-r108. PMC 4053738. PMID 23181666.