Phosphatidylinositol glycan anchor biosynthesis class W is a protein that in humans is encoded by the PIGW gene. [5]

PIGW
Identifiers
AliasesPIGW, Gwt1, HPMRS5, phosphatidylinositol glycan anchor biosynthesis class W
External IDsOMIM: 610275; MGI: 1917575; HomoloGene: 6243; GeneCards: PIGW; OMA:PIGW - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_178517
NM_001346754
NM_001346755

NM_001077636
NM_027388
NM_001363112

RefSeq (protein)

NP_001333683
NP_001333684
NP_848612

NP_001071104
NP_081664
NP_001350041

Location (UCSC)Chr 17: 36.53 – 36.54 MbChr 11: 84.77 – 84.77 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al., 2003 [PubMed 14517336]).

References

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  1. ^ a b c ENSG00000277161 GRCh38: Ensembl release 89: ENSG00000275600, ENSG00000277161Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045140Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Phosphatidylinositol glycan anchor biosynthesis class W". Retrieved 2016-10-29.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.