PDZRN3

PDZ domain-containing RING finger protein 3 is a protein that in humans is encoded by the PDZRN3 gene.

PDZRN3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1UHP, 1WH1
Identifiers
Aliases	PDZRN3, LNX3, SEMACAP3, SEMCAP3, PDZ domain containing ring finger 3
External IDs	OMIM: 609729 MGI: 1933157 HomoloGene: 10328 GeneCards: PDZRN3
Gene location (Human) Chr. Chromosome 3 (human) Band 3p13 Start 73,382,431 bp End 73,624,941 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band 6|6 D3 Start 101,126,570 bp End 101,354,858 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in hair follicle gastric mucosa urethra vastus lateralis muscle seminal vesicula saphenous vein right ventricle tibia parotid gland popliteal artery Top expressed in molar soleus muscle tibialis anterior muscle vastus lateralis muscle gastrocnemius muscle belly cord atrioventricular valve triceps brachii muscle sternocleidomastoid muscle temporal muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function zinc ion binding metal ion binding ubiquitin protein ligase activity ubiquitin-protein transferase activity transferase activity Cellular component neuromuscular junction nucleus nucleoplasm cytosol cytoplasm cell junction synapse Biological process neuromuscular junction development protein ubiquitination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23024 55983 Ensembl ENSG00000121440 ENSMUSG00000035357 UniProt Q9UPQ7 Q69ZS0 RefSeq (mRNA) NM_015009 NM_001303139 NM_001303140 NM_001303141 NM_001303142 NM_018884 RefSeq (protein) NP_001290068 NP_001290069 NP_001290070 NP_001290071 NP_055824 NP_061372 Location (UCSC) Chr 3: 73.38 – 73.62 Mb Chr 6: 101.13 – 101.35 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Bach I, Rodriguez-Esteban C, Carrière C, et al. (1999). "RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex". Nat. Genet. 22 (4): 394–9. doi:10.1038/11970. PMID 10431247. S2CID 22326394.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Katoh M, Katoh M (2004). "Identification and characterization of PDZRN3 and PDZRN4 genes in silico". Int. J. Mol. Med. 13 (4): 607–13. doi:10.3892/ijmm.13.4.607. PMID 15010864.
• Hassel S, Eichner A, Yakymovych M, et al. (2004). "Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry". Proteomics. 4 (5): 1346–58. doi:10.1002/pmic.200300770. PMID 15188402. S2CID 6773754.
• Santin AD, Zhan F, Bellone S, et al. (2004). "Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: identification of candidate molecular markers for ovarian cancer diagnosis and therapy". Int. J. Cancer. 112 (1): 14–25. doi:10.1002/ijc.20408. PMID 15305371. S2CID 29845339.
• Meyer G, Varoqueaux F, Neeb A, et al. (2005). "The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin". Neuropharmacology. 47 (5): 724–33. doi:10.1016/j.neuropharm.2004.06.023. PMID 15458844. S2CID 11771522.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.