P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.[5]

P2RY14
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesP2RY14, BPR105, GPR105, P2Y14, purinergic receptor P2Y14
External IDsOMIM: 610116; MGI: 2155705; HomoloGene: 15769; GeneCards: P2RY14; OMA:P2RY14 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001081455
NM_014879

RefSeq (protein)

NP_001074924
NP_055694

Location (UCSC)Chr 3: 151.21 – 151.28 MbChr 3: 59.02 – 59.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The product of this gene, P2Y14 belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.[5]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000174944Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036381Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: P2RY14 purinergic receptor P2Y, G-protein coupled, 14".

Further reading

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  • "P2Y Receptors: P2Y14". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2016-03-03. Retrieved 2008-12-09.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.