OTU deubiquitinase 1 is a protein that in humans is encoded by the OTUD1 gene. [5]

OTUD1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesOTUD1, DUBA7, OTDC1, OTU deubiquitinase 1
External IDsOMIM: 612022; MGI: 1918448; HomoloGene: 45953; GeneCards: OTUD1; OMA:OTUD1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001145373

NM_027715

RefSeq (protein)

NP_001138845

NP_081991

Location (UCSC)Chr 10: 23.44 – 23.44 MbChr 2: 19.66 – 19.67 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. DUBA7 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000165312Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043415Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: OTU deubiquitinase 1". Retrieved 2016-03-13.
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  • PDBe-KB provides an overview of all the structure information available in the PDB for Human OTU domain-containing protein 1

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.