OR10J3

Olfactory receptor 10J3 is a protein that in humans is encoded by the OR10J3 gene.

OR10J3
Identifiers
Aliases	OR10J3, OR1-25, OR10J3P, olfactory receptor family 10 subfamily J member 3
External IDs	MGI: 3030052; HomoloGene: 105155; GeneCards: OR10J3; OMA:OR10J3 - orthologs
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1|1 H3 Start 173,025,375 bp End 173,033,903 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle prefrontal cortex brain esophagus cerebral cortex multicellular organism n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 441911 258880 Ensembl n/a ENSMUSG00000046643 UniProt Q5JRS4 E9PWV2 RefSeq (mRNA) NM_001004467 NM_001001809 NM_146880 RefSeq (protein) NP_001004467 NP_001001809 Location (UCSC) n/a Chr 1: 173.03 – 173.03 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.135.3652. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.

External links

• OR10J3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.