Nuclear mitotic apparatus protein 1

Nuclear mitotic apparatus protein 1 is a protein that in humans is encoded by the NUMA1 gene.[5][6]

NUMA1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNUMA1, NUMA, NMP-22, nuclear mitotic apparatus protein 1
External IDsOMIM: 164009; MGI: 2443665; HomoloGene: 38150; GeneCards: NUMA1; OMA:NUMA1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001286561
NM_006185

NM_133947

RefSeq (protein)

NP_001273490
NP_006176
NP_006176.2

Location (UCSC)Chr 11: 72 – 72.08 MbChr 7: 101.58 – 101.66 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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Nuclear mitotic apparatus protein 1 has been shown to interact with PIM1,[7] Band 4.1,[8] GPSM2[9] and EPB41L1.[10]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000137497Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000066306Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Sparks CA, Bangs PL, McNeil GP, Lawrence JB, Fey EG (Oct 1993). "Assignment of the nuclear mitotic apparatus protein NuMA gene to human chromosome 11q13". Genomics. 17 (1): 222–224. doi:10.1006/geno.1993.1307. PMID 8406455.
  6. ^ "Entrez Gene: NUMA1 nuclear mitotic apparatus protein 1".
  7. ^ Bhattacharya N, Wang Zeping, Davitt Christine, McKenzie Ian F C, Xing Pei-Xiang, Magnuson Nancy S (Jul 2002). "Pim-1 associates with protein complexes necessary for mitosis". Chromosoma. 111 (2). Germany: 80–95. doi:10.1007/s00412-002-0192-6. ISSN 0009-5915. PMID 12111331. S2CID 26016943.
  8. ^ Mattagajasingh SN, Huang S C, Hartenstein J S, Snyder M, Marchesi V T, Benz E J (Apr 1999). "A nonerythroid isoform of protein 4.1R interacts with the nuclear mitotic apparatus (NuMA) protein". J. Cell Biol. 145 (1). UNITED STATES: 29–43. doi:10.1083/jcb.145.1.29. ISSN 0021-9525. PMC 2148212. PMID 10189366.
  9. ^ Du Q, Stukenberg P T, Macara I G (Dec 2001). "A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization". Nat. Cell Biol. 3 (12). England: 1069–1075. doi:10.1038/ncb1201-1069. ISSN 1465-7392. PMID 11781568. S2CID 7955950.
  10. ^ Ye K, Compton D A, Lai M M, Walensky L D, Snyder S H (Dec 1999). "Protein 4.1N binding to nuclear mitotic apparatus protein in PC12 cells mediates the antiproliferative actions of nerve growth factor". J. Neurosci. 19 (24). UNITED STATES: 10747–56. doi:10.1523/JNEUROSCI.19-24-10747.1999. PMC 6784956. PMID 10594058.

Further reading

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  • Overview of all the structural information available in the PDB for UniProt: Q14980 (Nuclear mitotic apparatus protein 1) at the PDBe-KB.