Normacusine B (vellosiminol) is a hypotensive isolate of Strychnos atlantica.[1]

Normacusine B
Names
IUPAC name
[(15Z)-15-ethylidene-3,17-diazapentacyclo[12.3.1.02,10.04,9.012,17]octadeca-2(10),4,6,8-tetraen-13-yl]methanol
Other names
Vellosiminol; Tombozine; Sarpagan-17-ol
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C19H22N2O/c1-2-11-9-21-17-8-14-12-5-3-4-6-16(12)20-19(14)18(21)7-13(11)15(17)10-22/h2-6,13,15,17-18,20,22H,7-10H2,1H3/b11-2+
    Key: VXTDUGOBAOLMED-BIIKFXOESA-N
  • C/C=C/1\CN2C3CC1C(C2CC4=C3NC5=CC=CC=C45)CO
Properties
C19H22N2O
Molar mass 294.398 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References

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  1. ^ Oliveira, E. J; Medeiros, I. A; Mukherjee, R (1996). "Hypotensive and spasmolytic effects of normacusine B from Strychnos atlantica root". Phytomedicine. 3 (1): 45–9. doi:10.1016/S0944-7113(96)80009-2. PMID 23194860.