Nicotinic acid N-oxide

Nicotinic acid N-oxide is an organic compound with the formula (HO2C)C5H4NO. It is the N-oxide of nicotinic acid ((HO2C)C5H4N). It is prepared by oxidation of nicotinic acid or the hydrolysis of 3-cyanopyridine N-oxide. The compound is a precursor to the popular drugs niflumic acid and pranoprofen.[1]

Nicotinic acid N-oxide
Names
IUPAC name
1-oxidopyridin-1-ium-3-carboxylic acid
Other names
Oxiniacic acid
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.017.515 Edit this at Wikidata
EC Number
  • 219-265-0
UNII
  • InChI=1S/C6H5NO3/c8-6(9)5-2-1-3-7(10)4-5/h1-4H,(H,8,9)
    Key: FJCFFCXMEXZEIM-UHFFFAOYSA-N
  • C1=CC(=C[N+](=C1)[O-])C(=O)O
Properties
C6H5NO3
Molar mass 139.110 g·mol−1
Appearance colorless or white solid
Melting point 254.5 °C (490.1 °F; 527.6 K)
Hazards
GHS labelling:
GHS07: Exclamation mark
Warning
H312, H315, H319, H332
P261, P264, P271, P280, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P332+P313, P337+P313, P362, P363, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References

edit
  1. ^ Shimizu, Shinkichi; Watanabe, Nanao; Kataoka, Toshiaki; Shoji, Takayuki; Abe, Nobuyuki; Morishita, Sinji; Ichimura, Hisao (2000). "Pyridine and Pyridine Derivatives". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a22_399. ISBN 3527306730.