In enzymology, a neoxanthin synthase (EC 5.3.99.9) is an enzyme that catalyzes the chemical reaction:

Neoxanthin synthase
Identifiers
EC no.5.3.99.9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
violaxanthin neoxanthin

Hence, this enzyme has one substrate, violaxanthin, and one product, neoxanthin.

This enzyme belongs to the family of isomerases, specifically a class of other intramolecular oxidoreductases. The systematic name of this enzyme class is violaxanthin---neoxanthin isomerase (epoxide-opening). This enzyme is also called NSY. This enzyme participates in carotenoid biosynthesis - general.

References

edit
  • Beyer P; Hugueney, P; Schledz, M; Welsch, R; Frohnmeyer, H; Laule, O; Beyer, P (2000). "Identification of a novel gene coding for neoxanthin synthase from Solanum tuberosum". FEBS Lett. 485 (2–3): 168–72. doi:10.1016/S0014-5793(00)02193-1. PMID 11094161. S2CID 24056399.
  • Bouvier F, D'harlingue A, Backhaus RA, Kumagai MH, Camara B (2000). "Identification of neoxanthin synthase as a carotenoid cyclase paralog". Eur. J. Biochem. 267 (21): 6346–52. doi:10.1046/j.1432-1327.2000.01722.x. PMID 11029576.