NFAT activating protein with ITAM motif 1 is a protein that in humans is encoded by the NFAM1 gene. [5]

NFAM1
Identifiers
AliasesNFAM1, CNAIP, bK126B4.4, NFAT activating protein with ITAM motif 1
External IDsOMIM: 608740; MGI: 1921289; HomoloGene: 12528; GeneCards: NFAM1; OMA:NFAM1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_145912
NM_001318323
NM_001371362

NM_001271411
NM_001271412
NM_001271413
NM_001271414
NM_028728

RefSeq (protein)

NP_001305252
NP_666017
NP_001358291

NP_001258340
NP_001258341
NP_001258342
NP_001258343
NP_083004

Location (UCSC)Chr 22: 42.38 – 42.43 MbChr 15: 82.88 – 82.92 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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The protein encoded by this gene is a type I membrane receptor that activates cytokine gene promoters such as the IL-13 and TNF-alpha promoters. The encoded protein contains an Immunoreceptor tyrosine-based activation motif (ITAM) and is thought to regulate the signaling and development of B-cells. [provided by RefSeq, Jul 2008].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000235568Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000058099Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: NFAT activating protein with ITAM motif 1". Retrieved 2018-03-13.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.