NCOA7

Nuclear receptor coactivator 7 is a protein that in humans is encoded by the NCOA7 gene.

NCOA7
Identifiers
Aliases	NCOA7, ERAP140, ESNA1, NCOA7-AS, Nbla00052, Nbla10993, TLDC4, dJ187J11.3, nuclear receptor coactivator 7
External IDs	OMIM: 609752 MGI: 2444847 HomoloGene: 65245 GeneCards: NCOA7
Gene location (Human) Chr. Chromosome 6 (human) Band 6q22.31-q22.32 Start 125,781,161 bp End 125,932,034 bp
Gene location (Mouse) Chr. Chromosome 10 (mouse) Band 10|10 A4 Start 30,504,995 bp End 30,679,322 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Brodmann area 23 pancreatic epithelial cell Brodmann area 46 middle temporal gyrus endothelial cell parietal pleura visceral pleura spinal ganglia pons cerebellar vermis Top expressed in cervix ventral tegmental area dorsomedial hypothalamic nucleus medial vestibular nucleus subiculum superior colliculus blood dorsal tegmental nucleus paraventricular nucleus of hypothalamus piriform cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding nuclear receptor coactivator activity Cellular component intracellular anatomical structure nucleus Biological process regulation of transcription, DNA-templated transcription, DNA-templated positive regulation of transcription by RNA polymerase II negative regulation of cellular response to oxidative stress negative regulation of peptidyl-cysteine S-nitrosylation negative regulation of oxidative stress-induced neuron death Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 135112 211329 Ensembl ENSG00000111912 ENSMUSG00000039697 UniProt Q8NI08 Q6DFV7 RefSeq (mRNA) NM_001122842 NM_001199619 NM_001199620 NM_001199621 NM_001199622 NM_181782 NM_001111267 NM_172495 NM_001358841 NM_001358842 RefSeq (protein) NP_001116314 NP_001186548 NP_001186549 NP_001186550 NP_001186551 NP_861447 NP_001104737 NP_766083 NP_001345770 NP_001345771 Location (UCSC) Chr 6: 125.78 – 125.93 Mb Chr 10: 30.5 – 30.68 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

See also

• Transcription coregulator

External links

• NURSA C96

Further reading

• Ohira M, Morohashi A, Nakamura Y, et al. (2003). "Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma". Cancer Lett. 197 (1–2): 63–8. doi:10.1016/S0304-3835(03)00085-5. PMID 12880961.
• Halachmi S, Marden E, Martin G, et al. (1994). "Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription". Science. 264 (5164): 1455–8. Bibcode:1994Sci...264.1455H. doi:10.1126/science.8197458. PMID 8197458.
• Nguyen TA, Hoivik D, Lee JE, Safe S (1999). "Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex". Arch. Biochem. Biophys. 367 (2): 250–7. doi:10.1006/abbi.1999.1282. PMID 10395741.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Rushing SR, Denison MS (2002). "The silencing mediator of retinoic acid and thyroid hormone receptors can interact with the aryl hydrocarbon (Ah) receptor but fails to repress Ah receptor-dependent gene expression". Arch. Biochem. Biophys. 403 (2): 189–201. doi:10.1016/S0003-9861(02)00233-3. PMID 12139968.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Durand M, Kolpak A, Farrell T, et al. (2007). "The OXR domain defines a conserved family of eukaryotic oxidation resistance proteins". BMC Cell Biol. 8: 13. doi:10.1186/1471-2121-8-13. PMC 1847813. PMID 17391516.

External links

• NCOA7+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.