N-acetylneuraminate epimerase

N-acetylneuraminate epimerase (EC 5.1.3.24, sialic acid epimerase, N-acetylneuraminate mutarotase, sialic acid mutarotase, YjhT, NanM) is an enzyme with systematic name N-acetyl-alpha-neuraminate 2-epimerase.[1] This enzyme catalyses the following chemical reaction

N-acetylneuraminate epimerase
Identifiers
EC no.5.1.3.24
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
N-acetyl-alpha-neuraminate N-acetyl-beta-neuraminate

Sialoglycoconjugates present in vertebrates are linked exclusively by alpha-linkages.

See also

edit

References

edit
  1. ^ Severi E, Müller A, Potts JR, Leech A, Williamson D, Wilson KS, Thomas GH (February 2008). "Sialic acid mutarotation is catalyzed by the Escherichia coli beta-propeller protein YjhT". The Journal of Biological Chemistry. 283 (8): 4841–9. doi:10.1074/jbc.M707822200. PMID 18063573.
edit