Myelonecrosis is a degenerative change to bone marrow caused primarily by loss of circulation to the bone tissue (ischaemia).[1]

These changes can be caused by toxic insult, thrombosis, neoplasia or DIC (disseminated intravascular coagulation).

References

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  1. ^ Prajapati, NC; Singh, T; Gautam, P; Dubey, AP; Choudhury, P; Puri, RK (1994). "Myelonecrosis in acute leukemia". Indian Pediatrics. 31 (1): 60–4. PMID 7883324.