Mohamed Khalifa may refer to:
- Mohamed Abdel Aziz Khalifa (born 1925), Egyptian swimmer
- Mohamed Asswai Khalifa (born 1944), Libyan hurdler
- Mohamed Khalifa (footballer) (born 1986), Egyptian footballer
- Mohamed Ould Khalifa (born 1968), Mauritanian long-distance runner
- Mohammed Jamal Khalifa (1957–2007), Saudi businessman
This disambiguation page lists articles about people with the same name.
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