Methanesulfonate monooxygenase (EC 1.14.13.111, mesylate monooxygenase, mesylate,reduced-FMN:oxygen oxidoreductase, MsmABCD, methanesulfonic acid monooxygenase, MSA monooxygenase, MSAMO) is an enzyme with systematic name methanesulfonate,NADH:oxygen oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction
| Methanesulfonate monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.111 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- methanesulfonate + NADH + H+ + O2 formaldehyde + NAD+ + sulfite + H2O
Methanesulfonate monooxygenase is a flavoprotein.
References
edit- ^ de Marco P, Moradas-Ferreira P, Higgins TP, McDonald I, Kenna EM, Murrell JC (April 1999). "Molecular analysis of a novel methanesulfonic acid monooxygenase from the methylotroph Methylosulfonomonas methylovora". Journal of Bacteriology. 181 (7): 2244–51. PMC 93639. PMID 10094704.
- ^ Higgins TP, Davey M, Trickett J, Kelly DP, Murrell JC (February 1996). "Metabolism of methanesulfonic acid involves a multicomponent monooxygenase enzyme". Microbiology. 142 ( Pt 2): 251–60. doi:10.1099/13500872-142-2-251. PMID 8932698.
External links
edit- Methanesulfonate+monooxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
