Martin O'Brien may refer to:
- Martin O'Brien (artist), British performance artist
- Martin O'Brien (journalist), Irish journalist
- Martin O'Brien (footballer) (1875–1946), Australian rules footballer
- Martin O'Brien (humanitarian) (born 1964), human rights activist and charity administrator in Northern Ireland
- Martin O'Brien (hurler) (1885–1958), Irish hurler
This disambiguation page lists articles about people with the same name.
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