In enzymology, a maltose-transporting ATPase (EC 3.6.3.19) is an enzyme that catalyzes the chemical reaction
| maltose-transporting ATPase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.6.3.19 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- ATP + H2O + maltoseout ADP + phosphate + maltosein
The 3 substrates of this enzyme are ATP, H2O, and maltose, whereas its 3 products are ADP, phosphate, and maltose.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (maltose-importing). This enzyme is a member of the ABC Transporter family.
Structural studies
editAs of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2AWN and 2AWO.
References
edit- Higgins CF (1992). "ABC transporters: from microorganisms to man". Annu. Rev. Cell Biol. 8: 67–113. doi:10.1146/annurev.cb.08.110192.000435. PMID 1282354.
- Dassa E, Muir S (1993). "Membrane topology of MalG, an inner membrane protein from the maltose transport system of Escherichia coli". Mol. Microbiol. 7 (1): 29–38. doi:10.1111/j.1365-2958.1993.tb01094.x. PMID 8437518. S2CID 86377074.
- Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146 (4): 271–8. doi:10.1016/0923-2508(96)81050-3. PMID 7569321.
- Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. Advances in Microbial Physiology. 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. ISBN 9780120277407. PMID 9889977.
- Griffiths JK; Sansom CE. "The Transporter Factsbook, Academic Press, San Diego, 1998".
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