MRGPRX3

Mas-related G-protein coupled receptor member X3 is a protein that in humans is encoded by the MRGPRX3 gene.

MRGPRX3
Identifiers
Aliases	MRGPRX3, GPCR, MRGX3, SNSR1, SNSR2, MAS related GPR family member X3
External IDs	OMIM: 607229; MGI: 3033148; HomoloGene: 79615; GeneCards: MRGPRX3; OMA:MRGPRX3 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11p15.1 Start 18,120,955 bp End 18,138,488 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 B3 Start 46,884,609 bp End 46,902,596 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in minor salivary glands olfactory zone of nasal mucosa lactiferous gland urinary bladder vagina ectocervix skin of leg smooth muscle tissue tibial nerve n/a More reference expression data BioGPS n/a
Gene ontology Molecular function signal transducer activity G protein-coupled receptor activity Cellular component plasma membrane membrane integral component of membrane integral component of plasma membrane Biological process G protein-coupled receptor signaling pathway signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 117195 668725 Ensembl ENSG00000179826 ENSMUSG00000074111 UniProt Q96LB0 n/a RefSeq (mRNA) NM_054031 NM_001370464 NM_001177566 NM_001288801 RefSeq (protein) NP_473372 NP_001357393 n/a Location (UCSC) Chr 11: 18.12 – 18.14 Mb Chr 7: 46.88 – 46.9 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

See also

• MAS1 oncogene

Further reading

• Lembo PM, Grazzini E, Groblewski T, et al. (2002). "Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs". Nat. Neurosci. 5 (3): 201–9. doi:10.1038/nn815. PMID 11850634. S2CID 42544746.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kaisho Y, Watanabe T, Nakata M, et al. (2005). "Transgenic rats overexpressing the human MrgX3 gene show cataracts and an abnormal skin phenotype". Biochem. Biophys. Res. Commun. 330 (3): 653–7. doi:10.1016/j.bbrc.2005.03.027. PMID 15809047.