MK5 may refer to:
- Mortal Kombat: Deadly Alliance, the fifth game in the Mortal Kombat series
- Mario Kart DS, the fifth game in the Mario Kart series, released in 2005 for the Nintendo DS
- MK5, an English postcode district
- British Rail Mark 5 (CAF), a rolling stock designation in the United Kingdom
- British Rail Mark 5A, a similar development of rolling stock in the United Kingdom
This disambiguation page lists articles associated with the same title formed as a letter–number combination.
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