E3 ubiquitin-protein ligase MIB1 is an enzyme that in humans is encoded by the MIB1 gene.[5] It is involved in regulating apoptosis.[6]

MIB1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMIB1, DIP-1, DIP1, LVNC7, MIB, ZZANK2, ZZZ6, mindbomb E3 ubiquitin protein ligase 1, MIB E3 ubiquitin protein ligase 1
External IDsOMIM: 608677; MGI: 2443157; HomoloGene: 10810; GeneCards: MIB1; OMA:MIB1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020774

NM_144860
NM_001364997

RefSeq (protein)

NP_065825

NP_659109
NP_001351926

Location (UCSC)Chr 18: 21.7 – 21.87 MbChr 18: 10.73 – 10.82 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Confusion with proliferative marker

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An antibody directed at the protein Ki-67, a product of the MKI67 gene, is called MIB-1.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000101752Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024294Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "MIB1 MIB E3 ubiquitin protein ligase 1 [ Homo sapiens (human) ]". Retrieved 6 July 2023.
  6. ^ MIB1. OMIM.URL: https://www.ncbi.nlm.nih.gov/omim/?term=608677. Accessed on: April 24, 2009.
  7. ^ MIB-1. Veripath OncoDiagnostics. http://www.oncodx.org/onco/mib_1.htm Archived 2006-05-28 at the Wayback Machine. Accessed on: April 24, 2009.

Further reading

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